Recent Publications


2020

RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon

Johnny Yu, Albertas Navickas, Hosseinali Asgharian, Bruce Culbertson, Lisa Fish, Kristle Garcia, John Paolo Olegario, Maria Dermit, Martin Dodel, Benjamin Hanisch, Yikai Luo, Ethan M Weinberg, Rodrigo Dienstmann, Robert S Warren, Faraz K Mardakheh and Hani Goodarzi. (2020)                                                                                                                                                                        Cancer Discovery (DOI: 10.1158/2159-8290.CD-19-1375)

https://cancerdiscovery.aacrjournals.org/content/early/2020/06/06/2159-8290.CD-19-1375

Maternal Larp6 controls oocyte development, chorion formation and elevation.

Hau HTA, Ogundele O, Hibbert AH, Monfries CAL, Exelby K, Wood NJ, Nevarez-Mejia J, Carbajal MA et al.(2020).

Development (Cambridge) vol. 147, (4)

10.1242/dev.187385


2019

Subcellular mRNA localization regulates ribosome biogenesis in migrating cells.

Dermit M , Dodel M , Lee FCY, Azman MS , Schwenzer H, Jones JL, Blagden SP, Ule J, Mardakheh FK* (2019). 

bioRxiv (CSHL).

doi: https://doi.org/10.1101/829739


2018

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.

Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, 

Bigot L et al.(2018).

Journal of Clinical Investigation vol. 128, (4) 1671-1687.

10.1172/JCI90277


2017

 
 
 
 

Mass spectrometry analysis of spatial protein networks by colocalization analysis (COLA).

Mardakheh FK(2017).  

Methods in Molecular Biology, vol. 1636, .

https://link.springer.com/protocol/10.1007/978-1-4939-7154-1_22 

 

Methods for monitoring and measurement of protein translation in time and space.

Dermit M, Dodel M, Mardakheh FK(2017). 

Molecular BioSystems vol. 13, (12) 2477-2488.

https://pubs.rsc.org/en/content/articlehtml/2017/mb/c7mb00476a


2016

 
 
 
 
 
 
 
 

RHO binding to FAM65A regulates Golgi reorientation during cell migration.

Mardakheh FK, Self A, Marshall CJ(2016). 
J Cell Sci vol. 129, (24) 4466-4479.
https://jcs.biologists.org/content/129/24/4466

NAMPT inhibition is a novel synthetic lethal therapeutic approach exploiting nuclear-mitochondrial crosstalk in ERCC1-deficient populations.

Touat M, Olaussen K, Sourisseau T, Friboulet L, Dorvault N, Enot D, Bigot L, Pontoizeau C et al. (2016). 

EUROPEAN JOURNAL OF CANCER. vol. 69, S56-S56.

10.1016/S0959-8049(16)32753-8

 

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).

Mardakheh FK, Sailem HZ, Kümper S, Tape CJ, McCully RR, Paul A, Anjomani-Virmouni S, Jørgensen C et al.(2016). 

Mol Biosyst vol. 13, (1) 92-105.

https://pubs.rsc.org/en/content/articlehtml/2017/mb/c6mb00701e

 

Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology–Genomic Integration Analysis.

Natrajan R, Sailem H, Mardakheh FK, Arias Garcia M, Tape CJ, Dowsett M, Bakal C, 

Yuan Y(2016). 

PLoS Medicine vol. 13, (2)

10.1371/journal.pmed.1001961

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.

Kümper S, Mardakheh FK, McCarthy A, Yeo M, Stamp GW, Paul A, Worboys J, 

Sadok A et al.(2016). 

eLife vol. 5, (JANUARY2016)

10.7554/eLife.12203.001


2015

 

Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions. 

Mardakheh FK, Paul A, Kümper S, Sadok A, Paterson H, Mccarthy A, Yuan Y, 

Marshall CJ(2015). 

Developmental Cell vol. 35, (3) 344-357.

10.1016/j.devcel.2015.10.005

Rho kinase inhibitors block melanoma cell migration and inhibit metastasis.

Sadok A, McCarthy A, Caldwell J, Collins I, Garrett MD, Yeo M, Hooper S, Sahai E et al.(2015). Cancer Research vol. 75, (11) 2272-2284.

10.1158/0008-5472.CAN-14-2156