Selected Publications


2021

A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements

Fish L, Khoroshkin M, Navickas A, Garcia K, Culbertson B, Hänisch B, Zhang S, Nguyen HCB, Soto LM, Dermit M, Mardakheh FK, Molina H, Alarcón C, Najafabadi HS, Goodarzi H. (2021)

Science 14;372(6543).
(DOI: 10.1126/science.abc7531)

https://science.sciencemag.org/content/372/6543/eabc7531.long

Purification and quantitative proteomic analysis of cell bodies and protrusions

Dermit M*  & Mardakheh FK* (2021)


STAR Protocols  2, 2, 100462

(DOI:  https://doi.org/10.1016/j.xpro.2021.100462)


2020



Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells

Dermit M , Dodel M , Lee FCY, Azman MS , Schwenzer H, Jones JL, Blagden SP, Ule J, Mardakheh FK* (2020)                                                                                                                                                                     Developmental Cell 35, 3, 298-313.

(DOI: https://doi.org/10.1016/j.devcel.2020.10.006)


RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon

Johnny Yu, Albertas Navickas, Hosseinali Asgharian, Bruce Culbertson, Lisa Fish, Kristle Garcia, John Paolo Olegario, Maria Dermit, Martin Dodel, Benjamin Hanisch, Yikai Luo, Ethan M Weinberg, Rodrigo Dienstmann, Robert S Warren, Faraz K Mardakheh and Hani Goodarzi. (2020)                                                                                                                                                                        Cancer Discovery (DOI: 10.1158/2159-8290.CD-19-1375)

https://cancerdiscovery.aacrjournals.org/content/early/2020/06/06/2159-8290.CD-19-1375

Maternal Larp6 controls oocyte development, chorion formation and elevation.

Hau HTA, Ogundele O, Hibbert AH, Monfries CAL, Exelby K, Wood NJ, Nevarez-Mejia J, Carbajal MA et al.(2020).

Development (Cambridge) vol. 147, (4)

10.1242/dev.187385


2019

Subcellular mRNA localization regulates ribosome biogenesis in migrating cells.

Dermit M , Dodel M , Lee FCY, Azman MS , Schwenzer H, Jones JL, Blagden SP, Ule J, Mardakheh FK* (2019). 

bioRxiv (CSHL).

doi: https://doi.org/10.1101/829739


2018

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.

Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, 

Bigot L et al.(2018).

Journal of Clinical Investigation vol. 128, (4) 1671-1687.

10.1172/JCI90277


2017

Methods for monitoring and measurement of protein translation in time and space.

Dermit M, Dodel M, Mardakheh FK(2017). 

Molecular BioSystems vol. 13, (12) 2477-2488.

https://pubs.rsc.org/en/content/articlehtml/2017/mb/c7mb00476a


2016

 
 
 
 
 
 
 
 

RHO binding to FAM65A regulates Golgi reorientation during cell migration.

Mardakheh FK, Self A, Marshall CJ(2016). 
J Cell Sci vol. 129, (24) 4466-4479.
https://jcs.biologists.org/content/129/24/4466

 

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).

Mardakheh FK, Sailem HZ, Kümper S, Tape CJ, McCully RR, Paul A, Anjomani-Virmouni S, Jørgensen C et al.(2016). 

Mol Biosyst vol. 13, (1) 92-105.

https://pubs.rsc.org/en/content/articlehtml/2017/mb/c6mb00701e

 

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.

Kümper S, Mardakheh FK, McCarthy A, Yeo M, Stamp GW, Paul A, Worboys J, Sadok A et al.(2016). 

eLife vol. 5, (JANUARY2016)

10.7554/eLife.12203.001


2015

 

Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions. 

Mardakheh FK, Paul A, Kümper S, Sadok A, Paterson H, Mccarthy A, Yuan Y, Marshall CJ(2015). 

Developmental Cell vol. 35, (3) 344-357.

10.1016/j.devcel.2015.10.005